Lopinavir to atazanavir or darunavir switch in HIV-1-infected patients with dyslipidemia: an observational study
نویسندگان
چکیده
Methods Patients treated with LPV with undetectable viral load since 6 months were switched to ATZ or DRV if they have low density lipoprotein (LDL)>1.6 g/l with no other cardiovascular risk, LDL>1.3g/l with at least 1 cardiovascular risk, or high density lipoprotein (HDL) <0.35mmo/l. None of the patients had an additional lipid-lowering treatment since 3 months, and others antiretroviral treatment wasn’t modified.
منابع مشابه
Lipid-lowering agents for dyslipidemia in patients who were infected with HIV in Taoyuan, Taiwan
INTRODUCTION There is no doubt that highly active antiretroviral therapy (ART) has decreased the total mortality of HIV-infected populations drastically, and HIV has become a chronic and manageable condition. However, complications after long-term treatment of ART tarnished the great efforts. We aimed to study the effects of add-on lipid-lowering agents on ART for patients who developed hyperli...
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We determine phenotypic susceptibility of human immunodeficiency virus type 2 (HIV-2) isolates to amprenavir, atazanavir, darunavir, indinavir, lopinavir, nelfinavir, saquinavir, and tipranavir. Saquinavir, lopinavir, and darunavir are potent against wild-type HIV-2 isolates and should be preferred as first-line options for HIV-2-infected patients. Other protease inhibitors are less active agai...
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متن کاملHigh levels of atazanavir and darunavir in urine and crystalluria in asymptomatic patients.
OBJECTIVES Atazanavir has been associated with kidney stones and renal failure. We measured urine and plasma concentrations of recent protease inhibitors (PIs) and searched for PI crystals in the urine of asymptomatic patients. METHODS A cross-sectional analysis of HIV-infected patients taking ritonavir-boosted atazanavir 300 mg/day (ATV300/r), unboosted atazanavir 400 mg/day (ATV400), ritona...
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عنوان ژورنال:
دوره 13 شماره
صفحات -
تاریخ انتشار 2010